补充:只要查到国外申请的专利在利用同族专利查国内专利申请公开。
Another such method of treatment that has been proposed is that of administering a compound which blocks the aggregation of A.beta.. Compounds having this property include chelating agents such as clioquinol (Gouras and Beal, Neuron, 30 (2001), 641-2) and the compounds disclosed in WO 99/16741, in particular that known as DP-109 (Kalendarev et al, J. Pharm. Biomed. Anal., 24 (2001), 967-75). Other inhibitors of A.beta. aggregation include the compounds disclosed in WO 96/28471, WO 98/08868 and WO 00/052048, including the compound known as Apan.TM. (Praecis), WO 00/064420, WO 03/017994, WO 99/59571 and the compound known as Alzhemed.TM. (Neurochem), WO 00/149281 and the compositions known as PTI-777 and PTI-00703 (ProteoTech), WO 96/39834, WO 01/83425, WO 01/55093, WO 00/76988, WO 00/76987, WO 00/76969, WO 00/76489, WO 97/26919, WO 97/16194, and WO 97/16191. |